Opium, which maintains its historic spas to cure all illnesses, is one of the rare places to visit in Turkey. BC 4000 years from a known settlement since the Opium BC Line remains have been found from 2,500 years of civilization. Afterwards within the sovereignty of the Hittites Afyon, BC In the year 1200 came under the sovereignty of the Phrygian. BC Which was dominated by the Persians in 500's of years BC it was conquered by Alexander the Great in 300 years, has participated in the Macedonian territory. The death of Alexander the Great with Egypt, began a struggle between Babylon and Macedonian commanders. At the end of the struggle and the environment within the Babylonian domination BC 100 pcs in an Asian Empire was founded by a decision taken by the Roman Empire. The Roman rule seems to be based on being 400 years.